Effects of scavengers of superoxide radicals,hydrogen peroxide,singlet oxygen and hydroxyl radicals on malondialdehyde generation from arachidonic acid by bovine seminal vesicle microsomes |
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Authors: | J de Vries C N Verboom |
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Institution: | (1) Department of Medicinal Chemistry, De Boelelaan 1083, NL-1081 HV Amsterdam, (The Netherlands) |
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Abstract: | Summary Superoxide dismutase, catalase and sodium formate did not inhibit the formation of malondialdehyde (MDA) from arachidonic acid, suggesting that O
2
, H2O2 and OH. are not involved in the enzymatical oxidation of arachidonic acid. Sodium azide was found to be an inhibitor of MDA production. |
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