Amoeboid movement: A review and proposal of a ‘membrane ratchet’ model |
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Authors: | L. P. Bignold |
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Affiliation: | (1) Department of Pathology, University of Adelaide, G.P.O. Box 498, 5001 Adelaide, South Australia, (Australia) |
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Abstract: | Summary Diverse cell types, including Amoebae, leukocytes, embryonic cells and tumour cells move about on solid surfaces to accomplish such activities as feeding, bacterial destruction, embryological development and metastasis. Theories of the mechanism of this movement are reviewed and a model is proposed which invokes the existence of specific, laterally mobile, transmembranous structures in the cell membrane, which are reversibly adhesive for both the contractile apparatus of the cell internally, and the substratum externally. By this model, the movement of all these cell types can be explained. |
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Keywords: | Amoeboid movement Amoebae polymorphonuclear leukocytes cells |
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