| 4,5-二甲基呋喃氨基腈衍生物的合成及抗菌活性 |
| |
| 引用本文： | 李艳,吴鸣虎.4,5-二甲基呋喃氨基腈衍生物的合成及抗菌活性[J].河南师范大学学报(自然科学版),2011,39(2):102-105. |
| |
| 作者姓名： | 李艳 吴鸣虎 |
| |
| 作者单位： | 咸宁学院 化学与生命科学学院,湖北咸宁,437100 |
| |
| 基金项目： | 湖北省自然科学基金项目(2009CDB317) |
| |
| 摘 要： | 通过4,5-二甲基呋喃氨基腈与芳醛反应,制得希夫碱,再采用NaBH4还原,合成了8个新型的4,5-二甲基呋喃氨基腈衍生物.其结构经1H NMR,IR,EI—Ms分析证实.生物活性测试结果表明,目标化合物具有一定的抗菌活性.
|
| 关 键 词： | 呋喃氨基腈衍生物 合成 抗菌活性 |
Synthesis and Fungicidal Activity of 4,5-Dimethyl Furan Aminonitriles Derivatives |
| |
| LI Yan,WU Ming-hu.Synthesis and Fungicidal Activity of 4,5-Dimethyl Furan Aminonitriles Derivatives[J].Journal of Henan Normal University(Natural Science),2011,39(2):102-105. |
| |
| Authors: | LI Yan WU Ming-hu |
| |
| Institution: | (Department of Chemistry and Life Sciences,Xianning College,Xiannning 437100,China) |
| |
| Abstract: | Reaction of 4,5-dimethyl furan aminonitriles with aromatic aldehydes gives Schiff bases,which is reduced with NaBH4 to provide 8 new 4,5-dimethyl furan aminonitriles derivatives.Their structures are characterized by 1HNMR,IR,MS.The preliminary bioassays indicate that these compounds possess certain fungicidal activities against five kinds of fungi at a concentration of 200 mg/L. |
| |
| Keywords: | furan aminonitriles derivative synthesis fungicidal activity |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
