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TRH analogue with C-terminal thioamide group. Synthesis, receptor binding, TSH-releasing activity and alpha-MSH-releasing activity |
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| Authors: | M Kruszyński G Kupryszewski U Ragnarsson M Alexandrova V Strbak M C Tonon H Vaudry |
| Abstract: | A new TRH analogue containing a C-terminal thioamide group was synthesized. This peptide was shown to have receptor-binding affinity, and TSH- as well as alpha-MSH-releasing activities very similar to native TRH. |
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