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Ein Sensibilisator der therapeutischen Digitaliswirkung
Authors:Hans Handovsky
Affiliation:(1) Laboratorium der Universitätsfrauenklinik Gent, Belgien
Abstract:Summary Complexes of bivalent tin with polyoxybenzene-polysulfonic acids have a diuretic effect, when injected subcutaneously in dogs or rabbits. The same compounds also sensibilize the cardiotonic effect of digitalis-substances on the isolated heart or on fragments of the isolated heart as usually employed for testing digitalis-substances.In a small number of patients suffering from heart disease, a rapid increase of their till then lowered diuresis was induced through subcutaneous injections of a solution of the above mentioned tin complex.
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