| P物质在正常与致聋白腰文鸟前脑X区表达水平的差异研究 |
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| 引用本文： | 张颖,尉红季,孙颖郁,左明雪. P物质在正常与致聋白腰文鸟前脑X区表达水平的差异研究[J]. 北京师范大学学报(自然科学版), 2009, 45(4) |
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| 作者姓名： | 张颖 尉红季 孙颖郁 左明雪 |
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| 作者单位： | 北京师范大学生命科学学院; |
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| 基金项目： | 国家自然科学基金资助项目(30670685;30870307) |
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| 摘 要： | 通过免疫组织化学方法对正常和致聋不同时程的成年雄性白腰文鸟X区P物质的表达进行了定量分析,结果发现:致聋后鸟的X区P物质表达量显著减少.X区是鸣禽鸣唱学习的重要核团,P物质也是一种重要的神经调质,提示X区P物质可能参与了鸣禽鸣唱可塑性的调节或鸣唱模式的维持.
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| 关 键 词： | X区 P物质 致聋 消减平均灰度 |
DIFFERENT SUBSTANCE P EXPRESSION IN AREA X IN NORMAL AND DEAFENED BENGALESE FINCH |
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| ZHANG Ying,WEI Hongji,SUN Yingyu,ZUO Mingxue. DIFFERENT SUBSTANCE P EXPRESSION IN AREA X IN NORMAL AND DEAFENED BENGALESE FINCH[J]. Journal of Beijing Normal University(Natural Science), 2009, 45(4) |
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| Authors: | ZHANG Ying WEI Hongji SUN Yingyu ZUO Mingxue |
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| Affiliation: | College of Life Sciences;Beijing Normal University;100875;Beijing;China |
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| Abstract: | Substance P expression in area X in normal and deafened Bengalese finchs was analyzed by immunohistochemistry. It was found that substance P expression decreased significantly after deafening. Area X is an important nucleus of song learning,and substance P is an important neuro-modulator. These data suggest that substance P expression in area X is related to plasticity modulation or song model maintenance. |
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| Keywords: | area X substance P deafen subtracted mean gray value |
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