Preparation and properties of chitosan-VC loaded nano-silver-doped natural latex

As one kind of the modern medical devices, various catheters are commonly used in interventional therapy, but they are prone to infection in the human body, which is a defect in clinical treatment. At present, the commonly used catheters are mostly treated with antibacterial coatings on the rubber catheters. However, there are some problems for their application, such as, easy peeling of the coating and poor durability of antibacterial properties. In order to solve the above problems, a kind of nano-silver antibacterial agent reduced and stabilized by Vitamin C modified chitosan was prepared, and then added into natural latex to produce an antibacterial latex with antibacterial properties from the inside to the outside. The chemical properties, mechanical properties and antibacterial properties of the samples were characterized, and the antibacterial mechanism of VC modified chitosan/nano silver was analyzed. The results showed that the antibacterial rates of the latex samples against E. coli and S. aureus reached 97.38% and 98.45%.