病毒感染与肥胖

摘要: 肥胖是一种多病原疾病，病毒感染仅仅是引发肥胖的一种因素。已发现9 种病毒和生物因子与人类、动物肥 胖有关，尚有与肥胖有关的病毒和生物因子有待发现。“感染性肥胖”是一种新的概念，有助于人们将来生产出预 防肥胖的疫苗和抗病毒治疗药物。

Viral Infection and Obesity

Nine different viruses have been implicated in obesity in animal models,but their role in human obesity has not been established conclusively.Avian adenovirus SMAM-1 is the first virus to be implicated in human obesity.hAd-36 has been found to be more prevalent in obese humans.Chickens inoculated with hAd-37 had much more visceral fat and body fat.Rous-associated virus type 7 induces a syndrome in chickens characterized by stunting and obesity,clearly,not every case of obesity is of infectious origin.However,if a few pathogens can cause obesity,there may be more awaiting discovery.These data give a new perspective to the etiology of obesity and raise the possibility of infection as a contributing factor for obesity in some humans.When such a relationship between pathogens and human obesity is well established,vaccines or antimicrobial agents may be employed to prevent or treat some forms of obesity.