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基于Wistar大鼠动物实验的早期脂肪肝识别研究
引用本文:谢秀群,罗燕,全杰荣,陈科,林江莉.基于Wistar大鼠动物实验的早期脂肪肝识别研究[J].实验科学与技术,2012,10(5):1-3,82.
作者姓名:谢秀群  罗燕  全杰荣  陈科  林江莉
作者单位:1. 四川大学生物医学工程系,成都,610065
2. 四川大学华西医院超声诊断科,成都,610041
基金项目:国家自然科学基金项目资助(30870715,30970781)
摘    要:临床上对早期脂肪肝的准确诊断具有较大难度,文中采用Wistar大鼠动物实验数据,研究早期脂肪肝的识别方法。通过提取肝脏超声射频信号的多个特征参数及假设检验得到的最佳特征矢量,再利用BP神经网络结合模糊函数对脂肪肝程度进行量化。结果表明,正常肝和轻度脂肪肝的识别率分别为97.50和94.29,假阴性率和假阳性率分别为2.5和5.71。

关 键 词:超声射频信号  脂肪肝  BP神经网络  模糊函数

Research of Recognition of Mild Fatty Liver Based on Animal Experiment of Wistar Rat
XIE Xiu-qun,LUO Yan,QUAN Jie-rong,CHEN Ke,LIN Jiang-li.Research of Recognition of Mild Fatty Liver Based on Animal Experiment of Wistar Rat[J].Experiment Science & Technology,2012,10(5):1-3,82.
Authors:XIE Xiu-qun  LUO Yan  QUAN Jie-rong  CHEN Ke  LIN Jiang-li
Institution:1.Department of Biomedical Engineering,Sichuan University,Chengdu 610065,China; 2.Department of Ultrasound,West China Hospital of Sichuan University,Chengdu 610041,China)
Abstract:It' s difficult to diagnose mild fatty liver correctly in clinic,so the research of recognition of mild fatty liver by using animal experiment data of Wistar rat is proposed in this paper.Firstly several characteristic parameters are selected from ultrasound radiofrequency signal of livers,then hypothesis testing is used to obtain the best characteristic vector,finally BP neural network combined with Fuzzy function is used to quantify the degree of fatty livers.The results show that,the accuracy rates of classification is 97.50 and 94.29 for normal liver and mild fatty liver separately,and false negative rate and false positive rate is 2.5 and 5.71 separately.
Keywords:ultrasonic radiofrequency signal  mild fatty liver  neural network  fuzzy function
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