| 球状蛋白质中氨基酸残基的一种疏水性标度 |
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| 引用本文： | 金闻博,刘少民,戴亚,罗永娟.球状蛋白质中氨基酸残基的一种疏水性标度[J].合肥工业大学学报(自然科学版),1994(3). |
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| 作者姓名： | 金闻博 刘少民 戴亚 罗永娟 |
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| 作者单位： | 合肥经济技术学院 |
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| 摘 要： | 文章利用蛋白质可及性，建立了一种新的氨基酸流水性标度，得出了氨基酸残基因折叠所埋藏的平均可及面积与其Ｎｏｚａｋｉ－Ｔａｎｆｏｔｄ自由能变化ΔＧρ相关，残基可及性分数是疏水性的一种本征量度的结论，并分析讨论了有关问题．
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| 关 键 词： | 氨基酸，可及性，疏水性 |
A NEW SCALE OF HYDROPHOBICITY FOR AMINO ACID RESIDUES IN GLOBULAR PROTEINS |
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| Jin Wenbo, Liu Shaomin, Dai Ya, Luo Yonjuan.A NEW SCALE OF HYDROPHOBICITY FOR AMINO ACID RESIDUES IN GLOBULAR PROTEINS[J].Journal of Hefei University of Technology(Natural Science),1994(3). |
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| Authors: | Jin Wenbo Liu Shaomin Dai Ya Luo Yonjuan |
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| Institution: | Jin Wenbo; Liu Shaomin; Dai Ya; Luo Yonjuan |
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| Abstract: | On the basis of accessibility to solvent for residues within proteins,a new scale of hydrophobicity for amino acid resdues was derived in this article.It was concluded that the mean accessible area which a residue buries upon folding is correlated with the Nozaki-Tanford free energy and the fractional accessibility of a residue is an intrinsic measure of hydrophobictiy. Correlative questions are discussed. |
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| Keywords: | amino acid accessibility hydrophobicity |
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