Cross-reactive monoclonal antibodies to alcohol dehydrogenases |
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| Authors: | B G Talbot G Bilodeau |
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| Institution: | (1) Département de biologie, Faculté des sciences, Université de Sherbrooke, J1K 2R1 Sherbrooke, Québec, Canada |
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| Abstract: | Summary Three anti-horse liver alcohol dehydrogenase (HLADH) monoclonal antibodies are described. Two are specific for ADH and cross-react with class I and II enzymes from mouse, horse and Chinese hamster. They are specific for the native enzyme but do not inhibit enzyme activity except when combined at high concentration. The third antibody was isolated as a response to rabbit metallothionein. It binds metalloproteins and inhibits ADH activity. |
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| Keywords: | Monoclonal antibodies alcohol dehydrogenase |
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