Regioselectivity in the oxidative deamination of 2-methyl-1,4-diaminobutane catalyzed by diamine oxidases |
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Authors: | E Santaniello Ada Manzocchi P A Biondi Tatjana Simonic |
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Institution: | (1) Istituto di Chimica, Facoltà di Medicina, Università di Milano, Via Saldini, 50, I-20133 Milano, (Italy);(2) Istituto di Fisiologia Veterinaria e Biochimica, Università di Milano, Via Celoria, 10, I-20133 Milano, (Italy) |
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Abstract: | Summary Diamine oxidase from pea seedlings (PDAO) catalyzes the oxidation of 2-methyl-1,4-diaminobutane in a regioselective fashion, whereas diamine oxidase from pig kidney (KDAO) shows no regioselectivity for the same reaction.This work was supported by Ministero della Pubblica Istruzione . We thank Prof. A. Fiecchi and Prof. S. Ronchi for many helpful discussions. |
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