| 胎盘免疫调节因子的实验研究 |
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| 引用本文： | 张学荣,舒雨雁.胎盘免疫调节因子的实验研究[J].广西科学,1996,3(4):41-44. |
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| 作者姓名： | 张学荣 舒雨雁 |
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| 作者单位： | 广西医科大学蛇毒研究所 |
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| 摘 要： | 报道了改良的胎盘免疫调节因子（ＰＦ）提取方法，并对制备的ＰＦ理化性质，生物学活性，急性及长期毒性进行了系统的研究，结果表明ＰＦ由３个组分构成，分子量为３８００～５０００属核酸和多肽物质，性能稳定，有明显提高机体细胞免疫功能作用毒性试验证实ＰＦ无毒副作用，长期应用完全，初步临床应用结果提示ＰＦ对鼻咽癌，结核及慢性乙肝患者免疫功能提高作用。
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| 关 键 词： | 胎盘 免疫调节因子 肽 生物活性 毒性试验 |
| 收稿时间： | 1996/9/16 0:00:00 |
Experimental Study on Placenta Immunoregulatory Factor |
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| Zhang Xuerong and Shu Yuyan.Experimental Study on Placenta Immunoregulatory Factor[J].Guangxi Sciences,1996,3(4):41-44. |
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| Authors: | Zhang Xuerong and Shu Yuyan |
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| Institution: | The Snake Venom Research Institute of Guangxi Medical University, 6 Binhu Road, Nanning Guangxi, 530021 and The Snake Venom Research Institute of Guangxi Medical University, 6 Binhu Road, Nanning Guangxi, 530021 |
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| Abstract: | It was reported that an improved preparative methed of placenta immunoregulatory factor (PF).The physical and chemical property,biological activity,acute and chronic toxicity of prepared PF were studied systematically.The results showed that PF was composed of three compoments,those comerments had approximate molecular weight of about 3800~5000,belonging to low molecuar weight ribonucleic acid and peptide. Being of a stable property, PF could promoted cell immunolgic function.Toxcity test proved that PF had no side effect and was safe for long time use. Preliminary clinical application results indicated that PF could promote the immunologic function of patients with Nasophasingo cascinoma (NPC),tuberculosis and chronic hepatitis B. |
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| Keywords: | placenta immunoregulatory factor placenta peptide preparation property |
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