A thin-layer chromatographic assay for measuring pineal hydroxyindole-O-methyltransferase activity |
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Authors: | I. Nir N. Hirschmann |
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Affiliation: | (1) Department of Pharmacology and Experimental Therapeutics, Hebrew University Schools of Medicine and Pharmacy, P.O. Box 12065, Jerusalem, Israel |
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Abstract: | Summary A thin-layer chromatographic procedure for measuring pineal HIOMT activity is described, based on the methylation of NAS to melationin. The method enalbes simple and accurate determination in small alipuots from a single pineal organ homogenate. |
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