Host cell reactivation capacity of different strains ofE. coli B resistant or sensitive to ozone

Summary Host cell reactivation capacity for ozonated or irradiated phage was determined for different strains ofE. coli either more sensitive or resistant to ozone than the wild type strain. The results suggest that theozr gene product could be involved in the same repair pathway for ozone-induced lesions on DNA as thepolA gene. The possible involment of a specific endonuclease for these lesions is also considered.This research was sponsored by the National Sciences and Engineering Research Council of Canada. P.L.H. acknowledges a postgraduate scholarship from the NSERC of Canada.