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链霉素对鸟类听觉毛细胞损伤的研究
引用本文:董银兰,张海珠,邢士杰.链霉素对鸟类听觉毛细胞损伤的研究[J].山西师范大学学报,2005,19(4):67-70.
作者姓名:董银兰  张海珠  邢士杰
作者单位:山西师范大学生命科学学院,山西临汾041004
基金项目:本课题由山西师范大学自然科学基金资助.
摘    要:将健康成年虎皮鹦鹉(Melopsitiacus undelafusp)分成三批按120mg/kg的剂量连续注射链霉素15天,分别于停药后15天、30天、60天时处死,对照组不给任何药物.然后制作石蜡切片并用光镜观察,检测对比实验组与对照组之间的不同.结果表明随着时间增加,高毛细胞数目增加,是毛细胞再生的结果;而矮毛细胞数目减少,直接导致了听力敏感性降低.可见毛细胞的再生是有可能的.

关 键 词:虎皮鹦鹉  链霉素  毛细胞
文章编号:1009-4490(2005)04-0067-04
收稿时间:2005-05-30
修稿时间:2005年5月30日

Study of Damage of Streptomycin to Bird's Hearing Hair Cell
DONG Yin-lan, ZHANG Hai-zhu, XING Shi-jie.Study of Damage of Streptomycin to Bird''''s Hearing Hair Cell[J].Journal of Shanxi Teachers University,2005,19(4):67-70.
Authors:DONG Yin-lan  ZHANG Hai-zhu  XING Shi-jie
Abstract:To investigate the change of structure and function in healthy adulthood melopsitiacus undelafusp inner ear following streptomycin damage.The characteristic and meaning of the action to the inner toxicity can be discussed by the kind of antibiotics.First melopsitiacus undelafusp were given daily injection of streptomycin(120mg/kg)for 15 consecutive days.Then animals allowed to survive 15,30,60 days before they were killed.No drugs was given to the healthy melopsitiacus undelafusp.Second make the paraffin slice to observe in micscrope.Check the differences between the deaf and the undeaf.Contrust the birds in portrait.The results tell us: the number of THC has increased.Maybe the hair cell reproduced.But the number of SHC has decreased.The sensity of hearing have cut down..As the time goes,the hair cell of melopsitiacus undelafusp regenerated possibilily.
Keywords:Melopsitiacus undelafusp  Streptomycin  Hair cell
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