Contractile filaments in cells of regenerating tendon |
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| Authors: | F. Postacchini P. G. Natali L. Accinni E. Ippolito C. De Martino |
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| Affiliation: | (1) 2 Clinica Ortopedica, University of Rome, Rome;(2) Present address: Istituto Regina Elena for Cancer Research, viale Regina Elena 291, Rome;(3) C. N. R. Clinica Medica 2, University of Rome, I-00161 Roma, Italy |
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| Abstract: | Summary An extensive cytoplasmic fibrillar system has been observed in fibroblast-like cells of regenerating tendon. It consists of bundles of actin filaments, which often show a cross-striated appearance due to electron dense bodies occurring throughout their length. The functional role of this contractile apparatus seems to be related to the process of movement and orientation of the newly formed cells and to the retraction of the regenerating tendon.Work was supported by grant C. N. R. n. 75.01224.04–115.5479 from Consiglio Nazionale delle Ricerche, Italy.The authors are grateful to Dr G. F. Bottazzo, Dept. Immunology, Middlesex Hospital, London, for carrying out the absorption experiments with purified actin and to Miss M. Rita Nicotra, Miss Laura M. Vassallo and Mr Mario Termine for their technical assistance. |
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