| 肌红蛋白与药物作用的荧光光谱及同步荧光光谱研究——以盐酸洛美利嗪为例 |
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| 引用本文： | 朱西挺,冯玉英,顾晓天,张跃华. 肌红蛋白与药物作用的荧光光谱及同步荧光光谱研究——以盐酸洛美利嗪为例[J]. 南通大学学报(自然科学版), 2007, 6(2): 51-53 |
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| 作者姓名： | 朱西挺 冯玉英 顾晓天 张跃华 |
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| 作者单位： | 南通大学,化学化工学院,江苏,南通,226007;南京师范大学,分析测试中心,江苏,南京,210097 |
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| 摘 要： | 以荧光光谱法和同步荧光光谱法研究肌红蛋白与药物盐酸洛美利嗪在水溶液中的相互作用,结果显示随着体系中盐酸洛美利嗪的增多,它们的相互作用增强,为阐明药物特别是脑血管扩张药与蛋白质作用提供了理论依据.
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| 关 键 词： | 肌红蛋白 荧光光谱 同步荧光光谱 盐酸洛美利嗪 |
| 文章编号： | 1673-2340（2007）02-0051-03 |
| 修稿时间： | 2006-11-14 |
Interaction between Myoglobin and Medicine Shown by Fluorescence Spectra and Syhchronous Fluorescence Spectra: a Case Study of Lomerizine Hydrochloride |
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| ZHU Xi-ting,FENG Yu-ying,GU Xiao-tian,ZHANG Yue-hua. Interaction between Myoglobin and Medicine Shown by Fluorescence Spectra and Syhchronous Fluorescence Spectra: a Case Study of Lomerizine Hydrochloride[J]. Journal of Nantong University (Natural Science Edition), 2007, 6(2): 51-53 |
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| Authors: | ZHU Xi-ting FENG Yu-ying GU Xiao-tian ZHANG Yue-hua |
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| Affiliation: | 1.School of Chemistry and Chemical Engineering, Nantong University, Nantong 226007, China; 2.Analysis and Testing Center, Nanjing Normal University, Nanjing 210097, China |
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| Abstract: | The interaction between Myoglobin and Lomerizine Hydrochloride in aqueous solution was studied by using fluorescence spectra and synchronous fluorescence spectra.The result indicated that the interaction between Myoglobin and Lomerizine Hydrochloride strengthened with the increase of Lomerizine Hydrochloride.This work provided a theoretical basis for the interaction between medicines and protein. |
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| Keywords: | Myoglobin fluorescence spectra synchronous fluorescence spectra Lomerizine Hydrochloride |
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