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热量限制对大鼠血脂和血液脂联素含量的影响
引用本文:姚茂忠,符健,陈湛娟. 热量限制对大鼠血脂和血液脂联素含量的影响[J]. 海南师范大学学报(自然科学版), 2014, 0(4): 410-411
作者姓名:姚茂忠  符健  陈湛娟
作者单位:1. 海南医学院 海南省药物安全性评价研究中心,海南 海口,571199
2. 海南医学院 药学院,海南 海口,571199
摘    要:为了研究热量限制对大鼠血脂和脂联素含量的影响,将20只SD雄性大鼠,随机分为对照组(自由采食)和热量限制组(正常对照组摄食量的60%).实验共持续28周.28周末,各组大鼠腹主动脉采血测定生化指标和脂联素含量.结果表明,热量限制能够将大鼠血液总胆固醇和甘油三酯含量分别降低19.10%和2.33%,但差异均不显著(P〉0.05);热量限制能够将大鼠血清脂联素含量提高54.04%,将大鼠血浆脂联素含量提高83.15%(P〈0.05).结论:热量限制能够降低大鼠血脂并显著提高血液中脂联素含量.

关 键 词:热量限制  脂质  脂联素  大鼠

Effects of Caloric Restriction on Content of Blood Lipids and Adiponectin in Rats
YAO Maozhong,FU Jian,CHEN Zhanjuan. Effects of Caloric Restriction on Content of Blood Lipids and Adiponectin in Rats[J]. Journal of Hainan Normal University:Natural Science, 2014, 0(4): 410-411
Authors:YAO Maozhong  FU Jian  CHEN Zhanjuan
Affiliation:YAO Maozhong, FU Jian, CHEN Zhanjuan ( 1. Research Center for Drug Safety Evaluation of Hainan Province, Hainan Medical University, Haikou 571199, China; 2. School of Pharmaceutical Sciences, Hainan Medical University, Haikou 571199, China )
Abstract:To investigate effects of caloric restriction (CR) on the content of blood lipids and adiponectin in rats, 20 male Sprague-Dawley rats were randomly divided into ad libitum (AD) group and CR group (60% intake of ad group). The test lasts for 28 weeks. At the end of the test, blood sample were collected from abdominal aortic of all the rats. Then blood lipids and adiponectin were detected. Compared with the AD, blood total cholesterol and triglyceride were decreased by 19.10% and 2.33%, respectively, but the difference were not significant (P〉0.05); serum adiponeetin and plasma adiponectin were increased by 54.04% and 83.15% (P〈0.05). The results showed that caloric restriction could decrease blood lipids content and significantly increase blood adiponectin in rat.
Keywords:caloric restriction  lipids  adiponectin  rat
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