Effect of colicin E3 on leukemia cells P 388 in vitro |
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Authors: | J Fuska Alžbeta Fusková J Šmarda J Mach |
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Institution: | (1) Department of Environmental Chemistry and Technology, Slovak Technical University, CS-880 37 Bratislava, Czechoslovakia;(2) Present address: Department of Biology, Medical Faculty, J.E. Purkyn University, Brno;(3) Present address: Institute of Sera and Vaccines, Praha |
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Abstract: | Summary Proliferation of murine leukemia cells P388 is stimulated by less than 1.0 mg/ml colicin E3, while being inhibited by higher concentrations. By 1.6 mg/ml colicin E3, uptake of thymidine into cold TCA-precipitable fraction is decreased by 59% during 24 h, uptake of uridine by 29%. |
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