| 基于奇异值求通解方法进行基因调控网络构建 |
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| 引用本文： | 沈威,郑明,刘桂霞,邢翀,吴佳楠,周春光,周柚. 基于奇异值求通解方法进行基因调控网络构建[J]. 中南大学学报(自然科学版), 2012, 43(4): 1377-1381 |
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| 作者姓名： | 沈威 郑明 刘桂霞 邢翀 吴佳楠 周春光 周柚 |
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| 作者单位： | 1. 吉林大学计算机科学与技术学院,吉林长春,130012;北华大学计算机科学技术学院,吉林长春,132021
2. 吉林大学计算机科学与技术学院,吉林长春,130012 |
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| 基金项目： | 国家自然科学基金资助项目(60873146,60973092,60903097);国家高技术研究发展计划(“863”计划)项目(2009AA02Z307);吉林大学研究生创新基金资助项目(20111062,200903175);吉林省科技厅项目(20090116,20101589) |
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| 摘 要： | 在改进分解权值矩阵的微分方程模型基础上,引入奇异值分解方法来辅助运算.该算法不是通过奇异值分解的特解得到网络的最终结果,而是通过所算得的通解提供候选解集的方法,为微分方程模型算法缩短运算时间和提高结果精度.将本文算法与其他传统微分方程模型算法进行对比,验证结果表明:该算法的效率较高.
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| 关 键 词： | 奇异值分解 微分方程模型 基因调控网络 候选解集 通解 无标度网络 数学建模 |
Construction of gene regulatory network based on singular value decomposition for solution set |
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| SHEN Wei , ZHENG Ming , LIU Gui-xia , XING Chong , WU Jia-nan , ZHOU Chun-guang , ZHOU You. Construction of gene regulatory network based on singular value decomposition for solution set[J]. Journal of Central South University:Science and Technology, 2012, 43(4): 1377-1381 |
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| Authors: | SHEN Wei ZHENG Ming LIU Gui-xia XING Chong WU Jia-nan ZHOU Chun-guang ZHOU You |
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| Affiliation: | 1 (1.College of Computer Science and Technology,Jilin University,Changchun 130012,China; 2.College of Computer Science and Technology,Beihua University,Jilin 132021,China) |
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| Abstract: | The singular value decomposition method was introduced to calculate the network based on the improved decomposed weighted value differential equation model.Differently from the existing singular value decomposition model used for getting final network,the singular value decomposition method was used to get the solution set.The algorithm for simulation data and the real data were tested and compared with other algorithms.The results show that the proposed algorithm has high precision. |
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| Keywords: | singular value decomposition differential equation model gene regulatory network solution set general solution scale-free network mathematical model |
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