生物反应器培养细胞组织的机械刺激作用

生物反应器用于组织工程细胞的培养目前已经应用的比较广泛．为了构建与在体组织的结构和力学性能相同的工程组织，人们开始尝试使用一定的机械刺激添加到生物反应器中，这不仅对于人工组织的合成具有重要的意义，而且还可以加深人们对组织和细胞本身性质的了解．综述了国内外一些文献对于生物反应器中机械刺激添加的原理和具体方法的报道，并分析了有刺激添加的反应器未来的发展趋势．

Mechanical Stimuli in Bioreactors of Cell Culturing

The bioreactors are widely used in the cell culturing in tissue engineering. For the construction of similar structure and function tissue as in vivo, people begin to adding mechanical stimuli to the bioreactor. That is not only crucial for the fabrication of engineered tissues in vitro, but also can facilitate our understanding the characters of the live tissue. The review summarizes the major approaches for cell culture, using mechanical stimuli and bioreactors. Furthermore, the suggestions on the future developing of bioreactors are provided.