A new N-glucuronide metabolite of carbamazepine |
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| Authors: | J. E. Bauer N. Gerber R. K. Lynn R. G. Smith R. M. Thompson |
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| Affiliation: | (1) Department of Pharmacology, Medical School, University of Oregon Health Sciences Center, 97201 Portland, Oregon, USA;(2) The Oregon Graduate Center, 97201 Portland, Oregon, USA;(3) Present address: Department of Pediatrics, University of Indiana Medical School, 46202 Indianapolis, Indiana, USA |
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| Abstract: | Summary An N-glucuronide metabolite of carbamazepine was identified in the bile of the isolated perfused rat liver by means of permethylation, gas chromatography and mass spectrometry.This research was supported by grants from the National Institutes of Health (Nos. N01-NS-5-2328, AM-17665) and the James Whitcomb Riley Memorial Association (No. 74-15) and a grant from the Epilepsy, Foundation of America. |
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