The metabolism of methadone by cultured mammalian cells. |
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Authors: | P C Will W D Noteboom |
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Abstract: | Rat hepatoma tissue culture cells and mouse leukemic cells were found to metabolize 1-3H] methadone to at least 2 unidentified radioactive compounds. These results suggest that cultured cells may be useful models for studying methadone metabolism by specific cell types. |
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