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Genetic algorithm in DNA computing: A solution to the maximal clique problem
引用本文:LIYuan FANGChen OUYANGQi. Genetic algorithm in DNA computing: A solution to the maximal clique problem[J]. 科学通报(英文版), 2004, 49(9): 967-971. DOI: 10.1007/BF03184020
作者姓名:LIYuan FANGChen OUYANGQi
作者单位:CenterforTheoreticalBiologyandDepartmentofPhysics,PekingUni-versity.Beijing100871.China
摘    要:Genetic algorithm is one of the possible ways tobreak the limit of brute-force method in DNA computing.Using the idea of Darwinian evolution, we introduce a geneticDNA computing algorithm to solve the maximal clique prob-lem. All the operations in the algorithm are accessible withtoday‘s molecular biotechnoiogy. Our computer simulationsshow that with this new computing algorithm, it is possible toget a solution from a very small initial data pool, avoidingenumerating all candidate solutions. For randomly generatedproblems, genetic algorithm can give correct solution withina few cycles at high probability. Although the current speedof a DNA computer is slow compared with silicon computers,our simulation indicates that the number of cycles needed inthis genetic algorithm is approximately a linear function ofthe number of vertices in the network. This may make DNAcomputers more powerfully attacking some hard computa-tional problems.

关 键 词:遗传算法 DNA计算机 最大集团问题 生物分子计算机 容量

Genetic algorithm in DNA computing: A solution to the maximal clique problem
Yuan?Li,Chen?Fang,Qi?OuyangEmail author. Genetic algorithm in DNA computing: A solution to the maximal clique problem[J]. Chinese science bulletin, 2004, 49(9): 967-971. DOI: 10.1007/BF03184020
Authors:Yuan?Li,Chen?Fang,Qi?Ouyang  author-information"  >  author-information__contact u-icon-before"  >  mailto:qi@pku.edu.cn"   title="  qi@pku.edu.cn"   itemprop="  email"   data-track="  click"   data-track-action="  Email author"   data-track-label="  "  >Email author
Affiliation:LI Yuan, FANG Chen & OUYANG Qi Center for Theoretical Biology and Department of Physics, Peking Uni-versity, Beijing 100871, China
Abstract:Genetic algorithm is one of the possible ways to break the limit of brute-force method in DNA computing. Using the idea of Darwinian evolution, we introduce a genetic DNA computing algorithm to solve the maximal clique prob-lem. All the operations in the algorithm are accessible with todays molecular biotechnology. Our computer simulations show that with this new computing algorithm, it is possible to get a solution from a very small initial data pool, avoiding enumerating all candidate solutions. For randomly generated problems, genetic algorithm can give correct solution within a few cycles at high probability. Although the current speed of a DNA computer is slow compared with silicon computers, our simulation indicates that the number of cycles needed in this genetic algorithm is approximately a linear function of the number of vertices in the network. This may make DNA computers more powerfully attacking some hard computa-tional problems.
Keywords:DNA computer   genetic algorithm   NP-complete problem.
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