单次高原运动对人体氧化压力和代谢压力的急性影响研究

旨在讨论高原与低海拔环境下单次有氧耐力运动后造成氧化压力和代谢压力的差异.招募38名大学生(男生20人,女生18人,平均年龄21.5±1.5岁,平均身高168.9±10.5 cm,平均体质量59.3±12.6 kg),全部受试者均须在高原和低海拔两种环境下进行耐力蹬车运动,分析受试者静息状态,运动后即刻,运动后10 min,运动后60 min,运动后120 min,运动后240 min的血液生化指标变化.利用双因素方差分析检验两种环境下耐力运动后的血液生化指标差异.研究发现高原环境进行耐力训练后红细胞比容、乳酸、尿酸显著高于低海拔环境(p0.05).高原耐力运动后血浆总蛋白、羰基蛋白、硫代巴比妥酸反应物、氮氧化物浓度、超氧歧化酶、过氧化氢酶活性与低海拔相比差异无统计学意义(p0.05).认为急性高原耐力运动与在低海拔环境进行的耐力运动对机体造成的氧化压力基本一致,但代谢压力远大于低海拔环境.高原环境下耐力运动后运动员的葡萄糖浓度显著降低,红细胞比容显著上升,其可能与低氧环境下机体水分大量散失、造成血浆总量下降有关.

On Effects of Single Plateau Exercise on Human Oxidative Pressure and Metabolize Pressure

Studies have been done to compare the effects of high-altitude and sea-level acute endurance exercises on oxidative stress. 38 healthy subjects (20 men and 18 women, age:21.5±1.5 yrs, height:168.9±10.5cm, weight:59.3±12.6kg) have been recruited and randomly assigned to high-altitude or sea-level environment for acute endurance exercise. Blood samples have been collected at resting, post-exercise, post-exercise 10 min, post-exercise 60 min, post-exercise 120 min, and post-exercise 240 min for analyzing the plasma biochemical indicators. All data have been denoted by the mean±standard error. Repeated measures two-way analysis of variance was adopted to test the mean differences. The level of significance was set at p<0.05. Results show that environmental effects on hematocrit, lactate, uric acid andwere significantly higher at high altitude than those at sea level (p<0.05). After endurance exercise in high-altitude environment, total plasma proteins, carbonyl proteins, thiobarbituric acid reactive substance, nitrogen oxides concentrations, superoxide dismutase activity, glutathione peroxidase activityand catalase activityare non-significantly different from those in sea-level environment (p>0.05). It is concluded that acute endurance exercise at high altitude (2 400 m) might not cause oxidative stress, but would increase metabolic stress.