In vivo lipolytic action of glucagon in brown adipose tissue of warm-acclimatized and cold-acclimatized rats

Summary Glucagon infusion caused a marked increase of brown fat venous FFA concentration, but the extent of increase was less in cold-acclimatized rats than in warm-acclimatized ones. Systemic venous FFA was not appreciably influenced by glucagon. Propanolol did not modify the changes induced by glucagon.The authors wish to thank the Novo Industri A/S for the gift of glucagon. — Address of Tomie Ohno: College of School Health, Hokkaido University of Education, Asahikawa 070 (Japan).