Protective and immunostimulating activity of a low dose of cyclophosphamide in the experimental infection of mice with foot-and-mouth disease virus |
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Authors: | E L Portiansky W M DiGirolamo R P Laguens |
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Affiliation: | Cátedra de Patología II, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, Argentina. |
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Abstract: | Administration to mice of a low, non-immunosuppressive dose of cyclophosphamide 4 days before infection with foot-and-mouth disease virus decreases viral replication, enhances the immune response against the virus and prevents pancreatic damage. |
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