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Melatonin modulates apomorphine-induced rotational behaviour
Authors:S Burton  S Daya  B Potgieter
Institution:(1) School of Pharmaceutical Sciences, Rhodes University, 6140 Grahamstown, (South Africa);(2) Department of Biochemistry, Rhodes University, 6140 Grahamstown, (South Africa)
Abstract:Summary Prior melatonin administration (1 and 10 mg/kg b.wt) causes a significant reduction in apomorphine (1 mg/kg b.wt) induced rotational behaviour in both 6-hydroxydopamine and quinolinic acid lesioned rats.
Keywords:Melatonin  apomorphine  6-hydroxydopamine  quinolinic acid  rotational behaviour
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