Selectivity of alterations in skeletal fibers in chronic Chagas' disease of the mouse |
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| Authors: | P. M. Cabeza Meckert R. P. Laguens |
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| Affiliation: | (1) Catedra de Patologia II, Facultad de Ciencias Medicas, Universidad Nacional de la Plata, 1900 La Plata, Argentina |
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| Abstract: | Summary In mice chronically infected withTrypanosoma cruzi, the masseter muscle (rich in type II fibers) was devoid of inflammatory infiltrates and parasites. In contrast, other muscles, composed of type I and II fibers, showed a decrease of type I fibers, parasites and lesions, suggesting that inT. cruzi infection type I muscle fibers are selectively damaged. |
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| Keywords: | Trypanosoma cruzi Chagas' disease skeletal muscle tissue tropism |
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