N-cadherin detected in the membrane fraction of lens fiber cells |
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Authors: | H Maisel P Atreya |
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Institution: | Department of Anatomy/Cell Biology, Wayne State University, School of Medicine, Detroit, Michigan 48201. |
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Abstract: | N-cadherin was identified as a glycoprotein present in the fiber cell membranes of frog, chick, bovine, rabbit and human lenses. The molecular size of N-cadherin varies with the species. Homogenization of the chick lens in the presence of Ca2+ resulted in a decrease in the concentration of N-cadherin. This suggests that the lens contains a Ca2(+)-activated protease which can act on N-cadherin. |
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