Relevance of chlorine-substituent for the antifungal activity of syringomycin and syringotoxin,metabolites of the phytopathogenic bacteriumPseudomonas syringae pv.syringae |
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| Authors: | I Grgurina A Barca S Cervigni M Gallo A Scaloni P Pucci |
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| Institution: | (1) Dipartimento di Scienze Biochimiche  A. Rossi-Fanelli , Università La Sapienza di Roma, I-00185 Rome;(2) Dipartimento di Biochimica e di Biotecnologie Mediche, Università Federico II, I-80134 Naples;(3) Dipartimento di Chimica Organica e Biologica, Università Federico II, I-80134 Naples, Italy |
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| Abstract: | Structural analogues of syringomycin and syringotoxin were produced by fermentation, characterized by FAB-MS and amino acid analysis and compared to the parent compounds in the antibiosis test againstRhodotorula pilimanae. The C-terminal residue was shown to be important for the activity. |
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| Keywords: | Pseudomonas syringae pv syringae syringomycin syringotoxin structural analogues antibiotic activity |
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