用于细胞成像的便携型微流控芯片检测系统

针对微流控芯片检测装置普遍需要大型数码显微镜的问题,使用自行设计的一套嵌入式微流控芯片小型成像系统拍摄芯片管道中的细胞,并提出在该条件下细胞自动检测与识别的算法。首先,用球形波进行图像背景校正,然后用基于局部方差的直方图均衡化算法进行细胞目标增强,并作滤波和背景去除处理,最后用C anny算子检测细胞边缘并返回原图对细胞进行标记。结果表明:小型的微流控芯片检测系统和处理方法可以使整个片上系统实现更高的集成化、自动化和便携性。

Portable microfluidic chip detection system for cell images

Since digital microscopes for imaging microfluidic chip detectors are large and cumbersome,a portable embedded cell imaging system was designed to detect the microfluidic chip conditions with an algorithm for automatic testing and recognition of cells.The algorithm first uses spherical adjustment of background image,and then enhances the target cell image through local variance-based histogram equalization,after filtering the noise and removing the background image.Finally,a Canny operator is used for fragm...