Effect of prostaglandin E1 on rat gastric motility and cyclic nucleotide content |
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Authors: | N. L. Shearin W. L. Pancoe |
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Affiliation: | (1) Faculty of Medicine, Memorial University of Newfoundland, P. O. Box 129, A1C 5S7 St. John's, Newfoundland, Canada |
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Abstract: | Summary Administration of exogenous prostaglandin E1 resulted in an increase in contractility of rat fundic muscle measured in vivo; a significant decrease in fundic tissue levels of cyclic-adenosine monophosphate and a significant increase in cyclic-guanosine monophosphate. |
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