A specific endogenous inhibitor of two forms of Ca++ activated neutral proteases in platelets |
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Authors: | M Sakon T Tsujinaka J Kambayashi G Kōsaki |
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Institution: | (1) Hemostasis Research Unit, The 2nd Department of Surgery, Osaka University Medical School, Fukushima-ku, 553 Osaka, (Japan) |
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Abstract: | Summary An endogenous, specific inhibitor of high molecular weight has been isolated from bovine blood platelets, which inhibits the activity of the 2 forms of platelet Ca++ activated neutral proteases reported previously by us. The inhibition is not due to chelation of Ca++ but results from a stoichiometric complex formation. |
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