| 红细胞的钱串现象和变形性的关系 |
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| 引用本文： | 许红,游永东.红细胞的钱串现象和变形性的关系[J].复旦学报(自然科学版),1992,31(3):305-311. |
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| 作者姓名： | 许红 游永东 |
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| 作者单位： | 复旦大学生理学和生物物理学系，复旦大学生理学和生物物理学系，复旦大学生理学和生物物理学系 1991届硕士研究生 |
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| 摘 要： |
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| 关 键 词： | 血红蛋白 老化 红细胞 钱串 变形性 |
RELATIONSHIP BETWEEN FORMATION OF THE ROULEAU AND THE DEFORMABILITY IN ERYTHROCYTES |
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| Xu Hong,You Yongdong,Zhang Zhihong.RELATIONSHIP BETWEEN FORMATION OF THE ROULEAU AND THE DEFORMABILITY IN ERYTHROCYTES[J].Journal of Fudan University(Natural Science),1992,31(3):305-311. |
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| Authors: | Xu Hong You Yongdong Zhang Zhihong |
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| Institution: | Department of Physiology and Biophysics |
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| Abstract: | In this paper a new method was described for measurement of the erythrocyte deformability based on PEG-induced Rouleau formation. It was designed on the hypothesis of Osmo-elastic Coupling that explains the correlation between formation of PEG-induced Rouleau and deformability. This correlation was confirmed by means of modification factors of the deformablility and the erythrocytes became more and more difficult in formation of Rouleau through advanced aging.The new method was also used in studying the effect of different hemoglobin states on the erythrocyte deformability. It was found that both DeoxyHb and MetHb reduced the deformability of the erythrocytes. The physiological and pathological significances of these changes were also discussed. |
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| Keywords: | hemoglobin aging erythrocyte Rouleau deformability osmoelastic coupling |
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