Nosiheptide,a sulfur-containing peptide antibiotic isolated fromStreptomyces actuosus 40037 |
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| Authors: | F Benazet M Cartier J Florent C Godard G Jung J Lunel D Mancy C Pascal J Renaut P Tarridec J Theilleux R Tissier M Dubost L Ninet |
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| Institution: | (1) Rhône-Poulenc Industries, Recherche et Développement, Centre Nicolas Grillet, 13 quai Jules Guesde, F-94400 Vitry-sur-Seine, (France) |
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| Abstract: | Summary Nosiheptide (9671 R.P.) isolated fromStreptomyces actuosus 40037 (NRRL 2954) is a sulfur-containing polypeptidic antibiotic, quite different from all the other members of this family. Very active in vitro against gram-positive bacteria, it is inactive in vivo in experimentally infected mice. Not toxic, even at high dose, it may be used as a feed additive for chickens and pigs and it shows a favourable effect on the growth and conversion index. |
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