Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor |
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| Authors: | T Kubo K Fukuda A Mikami A Maeda H Takahashi M Mishina T Haga K Haga A Ichiyama K Kangawa |
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| Abstract: | Cloning and sequence analysis of DNA complementary to porcine cerebral messenger RNA encoding the muscarinic acetylcholine receptor predict the complete amino-acid sequence of this protein. Expression of the complementary DNA produced functional muscarinic receptor in Xenopus oocytes. The muscarinic receptor is homologous with the beta-adrenergic receptor and rhodopsin in both amino-acid sequence and suggested transmembrane topography. |
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