The effect of nicotine on ethanol-induced gastric ulcers in rats |
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| Authors: | C W Ogle C H Cho S H Wong |
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| Institution: | (1) Department of Pharmacology, Faculty of Medicine, University of Hong Kong, 5 Sassoon Road, (Hong Kong) |
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| Abstract: | Summary Nicotine, in concentrations of 5 and 25  g/ml drinking water, given ad libitum for 10 days, dose-dependently increased lesion formation and worsened ethanol-induced ulceration in rat stomachs. Daily fluid intake and b.wt gain were not adversely affected by nicotine pretreatment.The authors are grateful to Mr C.T. Luk for his skilled technical assistance. |
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| Keywords: | Nicotine ethanol gastric ulcers |
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