治疗输入性疟疾30例临床特征分析

目的了解输入性疟疾的临床特点、抗疟药治疗效果,为临床诊治提供参考依据.方法对收治的30例非洲务工疟疾患者的临床表现、实验室检查、治疗方案进行回顾性分析.结果血检疟原虫阳性19例,其中,恶性疟原虫6例,间日疟原虫5例,分型不详8例;30例中单用蒿甲醚治疗10例,青蒿琥酯治疗8例,双氢青蒿素哌喹片治疗5例,氯喹治疗1例,蒿甲醚联合双氢青蒿素哌喹片治疗6例;疗程最短2 d,最长15 d,所有病例最终均有效控制症状.结论输入性疟疾临床症状典型,有急性肝损害、急性血管内溶血、急性肾衰竭、脑型疟疾及肺病变等常见并发症,血检疟原虫阳性率较高,常用抗疟药物能有效控制症状.

Clinical Characteristics Analysis of 30 Cases of Imported Malaria

Objective To investigate the clinical characteristics of imported malaria and the therapeutic effect of anti-malaria to provide the reference for the clinical diagnosis of malaria. Method A retrospective analysis was performed on the clinical manifestations, laboratory examination and therapeutic regimens of 30 cases of Africa workers with malaria. Results The blood tests showed that there were 19 cases with positive plasmodium, of which there were 6 cases with P. falciparum and 5 cases with P. vivax, and types of 8 cases were unknown ; 10 cases among of 30 cases were treated with artemether alone, 8 cases with artesunate and 5 cases with dihydroartemisinin piperaquine tablets, one case with ehloroquine, and 6 cases with artemether combined with dihydroartemisinin piperaquine;The shortest treatment course was 2 d and the longest treatment course was 15 d. The symptoms of all cases were effectively controlled ultimately. Conclusion The typical clinical symptoms of imported malaria may be characterized by complications of acute liver injury, acute intravascular hemolysis, acute renal failure, cerebral malaria and pulmonary lesions. The positive rate of plasmodium by blood test is high and the commonly used antimalarial drugs can control the symptoms effectively.