Structure and toxicity of the alkaloids of Russian comfrey (Symphytum x uplandicum Nyman), a medicinal herb and item of human diet |
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| Authors: | C. C. J. Culvenor M. Clarke J. A. Edgar J. L. Frahn M. V. Jago J. E. Peterson L. W. Smith |
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| Affiliation: | (1) CSIRO, Division of Animal Health, Private Bag 1, 3052 Parkville, Victoria, (Australia) |
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| Abstract: | Summary Eight pyrrolizidine alkaloids of hepatotoxic type have been indentified in leaves ofSymphytum × uplandicum The combined alkaloids exhibit chronic hepatotoxicity in rats.The authors thank N. Anderton and P. Stewart for skilled assistance and V. Lord for statistical analyses. |
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