| 氨基酸对映体拆分的研究进展 |
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| 引用本文： | 张莹,张阳阳,杨奇,张锋,李洪江. 氨基酸对映体拆分的研究进展[J]. 辽宁大学学报(自然科学版), 2002, 29(3): 193-197,233 |
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| 作者姓名： | 张莹 张阳阳 杨奇 张锋 李洪江 |
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| 作者单位： | 1. 辽宁大学化学科学与工程学院,辽宁,沈阳,110036
2. 辽宁省医药工业研究院,辽宁,沈阳,110011 |
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| 摘 要： | 本文综述色谱法，毛细管电泳法和萃取法在分离氨基酸对映体方面的有关最新研究成果，讨论各种拆分方法的原理和影响因素。
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| 关 键 词： | 研究进展 氨基酸 对映体 非对照体 手性拆分 色谱法 毛细管电泳法 萃取法 分离原理 |
| 文章编号： | 1000-5846(2002)03-0193-05 |
Research Progresses on the Resolution Enantiomer of Amino Acid |
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| ZHANG Ying ,ZHANG Yang-yang ,YANG Qi ,ZHANG Feng ,LI Hong-jiang. Research Progresses on the Resolution Enantiomer of Amino Acid[J]. Journal of Liaoning University(Natural Sciences Edition), 2002, 29(3): 193-197,233 |
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| Authors: | ZHANG Ying ZHANG Yang-yang YANG Qi ZHANG Feng LI Hong-jiang |
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| Affiliation: | ZHANG Ying 1,ZHANG Yang-yang 1,YANG Qi 1,ZHANG Feng 1,LI Hong-jiang 2 |
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| Abstract: | Not only in the domain of medication,food and hygiene but for the research of polypeptide and asymmetric synthesis,the resolution of the enantiomer of amino acids is of important. Preferential crystallization process was used for enantionmer. Crystallization process, enzymatic method, chromatography(including liquid cromatogram, gaseous cromatogram, thin layer cromatogram, cromatogram, coordination cromatogram, ion exchange cromatogram.) capillary electrophoresis method and extration were also used for enantiomer. The reaserch and application of all these methods accelerate the development of chiral compounds. This paper summarized the research achievement of chromatography, capillary electrophoresis method and extraction method in this field,up to date. Also discussed the principle and the influence factor of each method. |
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| Keywords: | amino acid enantiomer chiral resoluton. |
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