Effects of penfluridol on dopamine-sensitive adenylate cyclase in corpus striatum and substantia nigra of rats |
| |
| Authors: | U Seeber K Kuschinsky |
| |
| Institution: | (1) Abteilung Biochemische Pharmakologie, Max-Planck-Institut für Experimentelle Medizin, Hermann-Rein-Strasse 3, D-34 Göttingen, Germany |
| |
| Abstract: | Summary Penfluridol, a neuroleptic with diphenylbutyl piperidine structure, blocked the dopamine-sensitive adenylate cyclase in homogenates of corpus striatum and substantia nigra of rats, probably by a competitive antagonism versus dopamine.Acknowledgment. We thank Dr P. Janssen (Beerse, Belgium) for a generous gift of penfluridol. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
