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Neuron numbers in hypothalamic nuclei in young,middle-aged and aged male rats |
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| Authors: | J. L. Sartin A. A. Lamperti |
| Affiliation: | (1) Institute of Aging, Temple University, School of Medicine, 3420 North Broad Street, 19140 Philadelphia, Pennsylvania, USA;(2) Department of Anatomy, Temple University, School of Medicine, 3420 North Broad Street, 19140 Philadelphia, Pennsylvania, USA;(3) Present address: Department of Physiology and Pharmacology, Auburn University, School of Veterinary Medicine, 36849 Auburn University, AL, USA |
| Abstract: | Summary Morphologic analysis of nine hypothalamic areas revealed significant decreases in the number of neurons per unit area in the ventral medial and arcuate nuclei. These data suggest that altered neuron numbers in the VMW and perhaps the ARC may participate in the well documented reductions in endocrine and neuroendocrine function observed in aging rats. |
| Keywords: | Hypothalamus neuron number aging neuroendocrinology |
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