Thyroid activity in response to some gonadal steroids in methallibure-treatedHeteropneustes fossilis (Bloch) |
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| Authors: | T P Singh R B Raizada |
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| Institution: | (1) Department of Zoology, Fish Endocrinology Laboratory, Banaras Hindu University, Varanasi, (India);(2) Present address: Pesticide Division, Industrial Toxicology Research Center, P.O. Box No. 80, Lucknow, (India) |
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| Abstract: | Summary Methallibure treatment is as effective as hypophysectomy in reducing thyroid activity inH. fossilis. Sex steroids (TP and EB) administration restored thyroid activity in methallibure-treated females to normal level, but failed to elicit any response in males. This drug seems to block TSH secretion and thyroid hormone synthesis inH. fossilis.Financial assistance in the form of SRF from ICAR, New Delhi to one of us (R.B.R.), gift of methallibure from ICI Ltd., UK and TSH from NIH, USA, to T.P.S. are gratefully acknowledged. |
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