Action de la Psilocybine sur le cerveau du lapin

Summary Psilocybin, the by-product of which Psilocin] has been identified as 4-hydroxy-dimethyl-tryptamine (4-HTP) develops in the waking rabbit a marked activation of the somatic behaviour and of the electrical brain activity. This stimulating action is due to a depression of the mediothalamic recruiting and moderating system rather than to an activation of the reticular arousal system. The electrophysiological effects of 4-HTP are compared with those of 5-HTP.