| 问号赖型钩端螺旋体的进化分析 |
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| 引用本文： | 王晓峰,王参军,汪浩.问号赖型钩端螺旋体的进化分析[J].云南大学学报(自然科学版),2006,28(3):231-235. |
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| 作者姓名： | 王晓峰 王参军 汪浩 |
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| 作者单位： | 1. 云南大学,数理学院,非线性复杂系统中心,云南,昆明,650091
2. 云南大学,数理学院,非线性复杂系统中心,云南,昆明,650091;宝鸡文理学院,物理系,陕西,宝鸡,721007 |
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| 基金项目： | 国家“973”计划部分资助项目(G2000077308) |
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| 摘 要： | 对问号赖型钩端螺旋体的复制基因进行了分析,引入以S为分歧时间的概念,通过对每个同义位点和非同义位点的核苷酸替代数目的比较,并利用最小二乘法进行了函数拟合,得出在早期复制基因受到相对松的净化选择,之后选择约束力不断增强并慢慢趋于稳定.
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| 关 键 词： | 问号赖型钩端螺旋体 复制基因 进化 同义替代 非同义替代 |
| 文章编号： | 0258-7971(2006)03-0231-04 |
| 修稿时间： | 2005年11月14 |
Evolution analysis of Leptospira interrogans serovar Lai |
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| WANG Xiao-feng,WANG Can-jun,WANG Hao.Evolution analysis of Leptospira interrogans serovar Lai[J].Journal of Yunnan University(Natural Sciences),2006,28(3):231-235. |
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| Authors: | WANG Xiao-feng WANG Can-jun WANG Hao |
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| Institution: | 1. Center for Nonlinear Complex Systems, College of Mathematics and Physics, Yunnan University, Kunming 650091, China;2. Department of Physics, Baoji University of Sciences and Arts, Baoji 721007, China |
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| Abstract: | It was studied that a analysis of duplicate genes of Leptospira interrogans serovar Lai.Through the concept of divergence time S,by means of comparing the rates of nucleotide substitution at replacement and silent sites by performing least-squares analysis,the result shows that early in their history,many gene duplicates experience a phase of relaxed purifying selection,subsequently selection constraint gradually increases and eventually tendsd to the stability. |
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| Keywords: | Leptospira interrogans serovar Lai gene duplication evolution nonsynonymous substitution synonymous substitution |
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