Effects of pregnancy on the glucose-induced insulin release from cultivated pancreatic islets of the rat |
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Authors: | Brigitte Ziegler M Ziegler H Fiedler |
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Institution: | (1) Zentralinstitut für Diabetes, Forschung und Behandlung «Gerhardt Katsch», DDR-2201 Karlsburg/Greifswald, (German Democratic Republic) |
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Abstract: | Summary 7-day-cultured islets from pregnant Wistar rats released at 5.6 mM glucose significantly more insulin than islets from nonpregnant rats, whereas in vivo this heigthened glucose sensitivity is lost 48 h post partum.Investigations carried out as a part of the Forschungsprojekt Diabetes mellitus und Fettstoffwechselstörungen supported by the Ministry of Health of German Democratic Republic. |
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