| 顺式（±）菊酸动力学拆分研究 |
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| 引用本文： | 钟民,陈良.顺式（±）菊酸动力学拆分研究[J].华东师范大学学报(自然科学版),1995(3). |
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| 作者姓名： | 钟民 陈良 |
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| 作者单位： | 华东师范大学化学系 |
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| 摘 要： | 本文研究了以（－）－ｔｒａｎｓ－２，２－二甲基－３－异丁烯基环丙烷甲醇为拆分剂对（±）－ｃｉｓ－２，２－二甲基－３－异丁烯基环丙烷羧酸（顺式（±）菊酸）的动力学拆分。研究表明此菊酸酯在２米，１０％ＤＣ－ＱＦ－１不锈钢色谱柱上可以得到完全分离。顺式（±）菊酸的两种立体异构体的酯化相对速率相差较大，本文研究了反应物比例，反应温度，反应时间对顺式（±）菊酸酯化产物的影响，选择较佳的反应条件，可以将顺式（±）菊酸的两种立体异构体分开。利用此反应对顺式（±）菊酸进行动力学拆分，获得（－）－顺式菊酸，其ｅ，ｅ值达９５％。
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| 关 键 词： | 菊酸，（－）－trans－2，2－二甲基－3－异丁烯基环丙烷甲醇，气相色谱分离，动力学拆分 |
The Kinetic Resolution of d, 1-cis Chrysanthemic Acid |
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| Zhong Min, Chen liang.The Kinetic Resolution of d, 1-cis Chrysanthemic Acid[J].Journal of East China Normal University(Natural Science),1995(3). |
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| Authors: | Zhong Min Chen liang |
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| Abstract: | Separation of the optical isomers of chrysanthemic acid has been carred out by gas chromatography. The diastereoisomeric esters of chrysanthemic acid with 1-trans chrysanthemol were separated on a column of 10% DC-QF-1 coated on Chromosorb W. The esterification speed of l-cis chrysanthemic acid with l-trans chrysanthemol was faster than that of d-cis chrysanthemic acid. According to it, the d, l-cis chrysanthemic acid has been resolved and l-cis chrysanthemic acid with 95% optical purity is obtained. |
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| Keywords: | chrysanthemic acid 1-trans chrysanthemol GC separation kinetic resolution |
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