Zur Kenntnis des Muscarins |
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| Authors: | C H Eugster P G Waser |
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| Institution: | (1) Chemisches Institut und Pharmakologisches Institut der Universität Zürich, Switzerland |
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| Abstract: | Summary The alkaloid muscarin was isolated from fly agaric. The analyses of crystallized salts (chloride, tetra-chloroaurate,Reinecke's salt) led to C9H20O2N+ as the simplest formula. The presence of aldehyde and tri-methyl-ammonium groups, which had been assumed hitherto, could not be proved. The quaternary nature of the nitrogen atom was shown. Pharmacological tests on frog heart, rabbit gut and cats show the purely peripheral parasympathomimetic effect of the smallest doses. |
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